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Alumis stock downgraded at Guggenheim (ALMS:NASDAQ)

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Guggenheim downgraded Alumis (ALMS) to Neutral from Buy after the company reported a mid-stage trial setback for its lead asset, envudeucitinib, in systemic lupus erythematosus, an autoimmune condition affecting multiple organs.

Noting that its Phase 2b LUMUS study failed in

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